Hardware Accelerator Design for Dynamic-Programming-Based Protein Sequence Alignment with Affine Gap Tracebacks

Published in 2019 IEEE Biomedical Circuits and Systems Conference (BioCAS), 2019

We propose an ASIC design for dynamic programming sequence alignment with affine-gap traceback. The architecture reduce memory usage for traceback by 25%. The design speed up pairwise alignment by 570x

Recommended citation: Lin, Mao-Jan, Yu-Cheng Li, and Yi-Chang Lu. "Hardware accelerator design for dynamic-programming-based protein sequence alignment with affine gap tracebacks." 2019 IEEE Biomedical Circuits and Systems Conference (BioCAS). IEEE, 2019.
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